Can a massive data project finally answer the biggest questions about medical cannabis? In Part 2 of our conversation with Dr. Johannes Thrul, we explore the National Cannabis Study, an ambitious effort to build a global repository of cannabis research and real-world patient data. From standardized tools like the Cannabis Use Questionnaire to combining datasets from multiple studies, this project aims to uncover how cannabis truly impacts conditions like chronic pain, anxiety, PTSD, and insomnia. With AI analysis, collaborative research, and a goal of 10,000 participants, the team hopes to transform fragmented cannabis studies into one powerful evidence base. Listen now to learn how this groundbreaking cannabis database could reshape the future of cannabis medicine.

What will it take for cannabis and natural compounds to truly enter the mainstream—from toothpaste to energy drinks? In Part 2 of Trevor and Kirk’s conversation with biotech financier and cannabis strategist David Traylor, they discuss how major corporations might explore integrating cannabinoids like CBN and CBD and other natural products into everyday consumer products. David explains how his Skunk Works Nature AI advisory group connects global companies with world-class experts in pharmacology, biotechnology, and regulatory strategy to develop cannabinoid and other natural product based innovations. From potential sleep-supporting CBN toothpaste, to the role of pharmacogenomics and personalized medicine, this episode explores how science, investment, and product development intersect in the cannabis, psychedelic and natural product sectors. Trevor and Kirk also unpack the broader forces shaping the cannabis industry—stigma, regulatory barriers, banking challenges, and the tension between single-molecule pharmaceutical approaches vs. whole-plant medicine. Could big brands like PepsiCo or Red Bull be the catalyst that finally normalizes cannabinoid ingredients in consumer products? And what role does fear, policy, and economics play in slowing cannabis acceptance? Listen now to learn how cannabis science, biotech innovation, and big-industry investment could reshape the future of medicine, consumer products, and natural compounds.

What if the fastest way to feel cannabis effects isn’t through your lungs… but through your nose? Trevor and Kirk explore the science behind a unique cannabis accessory: the Nozzr, a nasal inhalation device designed to deliver vaporized cannabis through the nose rather than the mouth. Inventor and Respiratory Therapist Yvette Webb shares how the idea emerged during the COVID-19 pandemic while researching terpene interactions with respiratory viruses. Drawing on respiratory therapy, aerosol physics, and cannabis pharmacology, she explains how nasal inhalation may deliver cannabinoids and terpenes faster, potentially improving onset time, reducing coughing, and enhancing terpene perception through the olfactory system. Trevor and Kirk discuss whether nasal inhalation could offer benefits for medical cannabis patients, including people with chronic pain, migraines, spasticity, or mobility challenges. Is nasal cannabis inhalation the next evolution in cannabis consumption—or just a fascinating experiment in delivery science? Listen now to learn how terpene science, respiratory therapy, and cannabis innovation collide in this unusual but thought-provoking conversation.

What happens when a medical cannabis patient turns her healing journey into a cannabis science business? Trevor and Kirk talk with Yvette Webb, a Respiratory Therapist whose battle with Multiple Sclerosis, chronic pain, and insomnia led her to explore cannabis beyond THC. Her research into terpenes, cannabinoid delivery, and transdermal cannabis topicals ultimately inspired the creation of Cream of the Crop Therapeutics. From terpene science and topical cannabis formulations to the challenges of Canada’s medical cannabis system, this episode explores how patient innovation and plant chemistry intersect in modern cannabis medicine. Listen now to discover how terpenes, cannabinoids, and real-world patient experiences are reshaping cannabis therapeutics.

Join us on this exciting reunion with our friends at High on Homegrown! It has been five long years since our first appearance on High on Homegrown found in our early days of Episode 60. Macky interviews Kirk and Trevor. They dive deep into the fascinating world of medical cannabis, podcasting, and a bunch of entertaining, random topics you will find most fascinating. Can dog poop get you high? Why is medical cannabis so expensive and hard to get in the UK? Why Kirk disagrees with the entire world as to the definition of a cannabis "overdose"? Whether you're a long-time listener or new to the community, this episode brings you a casual conversation from three people who understand cannabis.