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 The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA. It’s too bad we at Reefer MEDness don’t know anything about microRNA. But wait…We do! Hilal Kalkan, a post-doc at Laval University, talks to us about how microRNA and cannabinoid receptors are involved in the side effect of a common cholesterol medication. Come dive deep into the molecular workings of the endocannabinoid system with us!
Pop quiz! Name a condition that costs $2.5 Billion to the Canadian health care system per year, that causes 1 in 5 sufferers to lose or quit a job at some point during their life because of the disease and that 8 in 10 people with the disease were initially told their pain was normal before diagnosis? Welcome to the under-appreciated suffering of those people who have endometriosis. Dr. Genester Wilson-King MD FACOG, founder and Medical Director of Victory Rejuvenation Center, is a Board-Certified Obstetrician and Gynecologist with over 25 years of Clinical experience. We would have loved to pick her brain on Bio-Identical Hormone Replacement, Premenstrual Syndrome, breast-feeding and cannabis and so many other topics, but we don’t have a 14 hour podcast. We had Dr. Wilson-King review for us the causes and symptoms of endometriosis, how it is treated and how cannabis fits into the picture. She dropped bomb-shells on us like: Did you know endometriosis can affect such disparate tissues as the lung and the brain? Our brains are still spinning and you should strap in and listen.
Published in Episodes
Tuesday, 01 October 2024 13:49

E132 - Road Stories #5 - 2024

VanHoot is now traveling the roads of northern British Columbia. While Michelle is off filling their cupboards and cooler, Kirk and River explore the resale cannabis market in those small communities they visit. Kirk records some of the discussions collecting cannabis stories to better understand cannabis from the budtenders’ perspective.  In this episode, we learn: how cannabis is marketed day-to-day, is a part time job for busy people, and is also positively affecting smaller community.  At one point Kirk sniffs resale cannabis from Mason Jars envisioning the future farmgate access.  When you listen to a Road Story episode, you are transported into the continuing adventures of VanHoot and its occupants.

Monday, 23 September 2024 14:35

E131 - Road Stories #4 - 2024

Once again, Kirk is on the road collecting stories, and never knowing where a story will take him. This road trip is in British Columbia where infused pre-rolls are the hottest summer blitz. Join Kirk and his dog River as they collect stories from cannabis stores, a vape shop, and while standing in a parking lot. We learn how bud tenders gain knowledge of cannabis: being an exit drug, assisting pregnant women, curing cancer, or just chilling at a town council meeting. You just never know what a Road Story will teach you about cannabis use.

Kirk catches up with Ted Smith from the Victoria Cannabis Buyers Club and his organization’s ill-defined existence within a country of legalized cannabis. We hear how Ted’s dreams, for this timeworn cannabis compassion club, are close to fruition yet there lingers potential for a new set of fines and a visit from the Public Health Authority impeding the full potential of this caring organization. In this episode we learn how the clouds preventing Ted from flying high are not simply from his new smoking lounge but rather the various levels of bureaucracy he must manage when putting compassion into action

You’ve got a PhD with lots of lab and testing experience. It should be easy to start a cannabis testing lab, right? Well, not really. Aldwin Anterola found cannabis growers weren’t always interested in finding the accurate amount of cannabinoids like THC in their products, among other problems. So, Aldwin went back to school. The NIH (National Institutes of Health) have an entrepreneurship program to help scientists learn how to bring their skills and products to market. Along the way, Aldwin learned a lot about Cannabis Hyperemesis Syndrome (CHS) and even interviewed our co-host Trevor as part of his NIH entrepreneurship program project.

The mitochondria is the powerhouse of the cell. That is what we learned in high school biology. But what if it is more? What if the mitochondria has receptors on it for cannabinoids? What if mitochondria move around the cell? What if mitochondria help produce chemical signals for the cell? What if mitochondria are involved in such diverse processes as epilepsy, mental health and aging itself? Hunter Land, PhD walks us through mitochondria and cannabinoids and so much more. Our preconceived notions about the powerhouse of the cell were blown out of the water. Let's see if yours are too!

Friday, 19 July 2024 15:37

E127 - Lazslo Mechtler - Dementia

Do you know anyone with dementia? If you don’t, you will. We humans are living longer and healthier lives. There are more healthy 75 year old people alive now than there ever have been. However, the number of people with dementia is sky rocketing as well. Enter Dr. Mechtler… Dr. Lazslo Mechtler is the Medical Director of Dent Neurologic Institute, the Chief of Neuro-Oncology at Roswell Park Cancer Institute and is also the Director of the DENT Headache Center, Neuro-Oncology Center, and Cannabis Clinic.  Dr. Mechtler gives us a fantastic review of dementia, and Alzheimer’s disease. Then he talks about the work they are doing at the DENT Institute to treat dementia with cannabinoids.

One sunny evening in the summer of 2020, Kirk and Trevor had a meeting on Kirk's driveway. Even though all indoor meetings were taboo, they met someone bursting with excitement. Eric Greening's face lit up as he described the cannabis growing facility he envisioned building north east of Dauphin.  Four years, a pandemic, spiraling inflation and all the other unknown unknowns of building a facility and starting a business are now behind the persistent Mr. Greening. As proud Dauphinites, we are excited to say Greencraft Cannabis is now selling product! And.... after much pestering, we got a peek inside! Come with us on an audio tour of the facility. There is a cannabis "tree" whose trunk Trevor can't wrap his hand around, a sunset room with alien-looking golden light, the secrets of how you control tiny invaders when you can't use any pesticides, and so much more!

 So many amazing Canna-people, so little time. CannMed 24 was sublime! Here are the another batch of clips we got!

Ben Cameransi – Mingowood Pharmacal, LLC - Dr. Benjamin Cameransi, MD, DABA is a Board-Certified Anesthesiologist, with a entensive background in pain management. He has started four BioTech Companies. He was involved in the development of Ryanodex™, a treatment for Malignant Hyperthermia. But wait, there’s more… Acidic cannabinoids aren’t very stable when they are extracted and purified. Dr. Camersani’s team at Mingowood Pharmacal has a way to fix that.

Taz Turner - CordovaCann Corp - Taz has the top three attributes we look for in a guest. He knows where Manitoba is located. He’s a finance guy who spoke intelligently during his Capital Markets Panel. He is fun to chat to at a breakfast information session. Taz tells us how it is surprisingly difficult to get investment into the cannabis space in 2024. But, numbers and valuation guys like him (who also speak cannabis) are slowly convincing others that opportunities abound.

Melissa Moore - Professor, Cannabis Horticulture & Biology, SUNY Niagra Community College. Melissa Moore developed some of her horticultural chops in Northern California, but now passes on her knowledge in Buffalo, NY. She was very helpful getting pics of Trevor during his Capital Markets Panel and then she sparked some intense Aspergillus discussions. Professor Moore tells us why cleanliness is next to godliness in your grow room and, hear why Kirk is frothing at the mouth to pick her brain about how to grow plants better.

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