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Olga Kovalchuk PhD

Role of epigenetic dysregulation in carcinogenesis. Epigenetic regulation of the cancer treatment responses. Radiation epigenetics and role of epigenetic changes in genome stability and carcinogenesis. Radiation-induced oncogenic signaling Radiation-induced DNA damage, repair and recombination.

Thursday, 30 July 2020 10:25

E53 - Does CBD have COVID-19 ACE'd?

What were you doing during the start of the pandemic lock down?  Did you build a puzzle for the first time in year?  Did you get reacquainted with how stupid and long and frustrating monopoly is?  How about sour dough bread?  Did you make your first sour dough?  Dr. Igor Kovalchuk and his wife, Dr. Olga Kovalchuk from the University of Lethbridge were locked out of their labs too.  Their lock down side project was a little more ambitious.  They had been researching hundreds of cannabis extracts to see if these extracts reduced inflammation and might help treat conditions like multiple sclerosis, psoriasis, inflammatory bowel disease and rheumatoid arthritis.  During this forced pause in their research, they wondered in CBD rich cannabis extracts might be useful against SARS-CoV-2, the virus that causes COVID-19.  You want to hear what they found out.

 
 
Thursday, 15 August 2019 14:28

E33 - Liver Let Die? A CDB Story

"Marijuana Study Finds CBD Can Cause Liver Damage".  This article in Forbes by Mike Adams blew up on Cannabis Twitter.  What is the truth?  Does the ubiquitous CBD beat up on the poor defenceless liver?  Is this just junk science and hyperbole?  Well...we called up the study authors and asked them.  Get ready to be schooled by Dr. Igor Koturbash , Dr. Bill J. Gurly and Dr. Mitchell R. McGill.  This conversation goes through the basic science involved in toxicology studies for any new medication.  Get ready to nerd out on why mice are really livers with legs, acute vs chronic dosing studies and much more.  Spoiler alert... these highly educated gentlemen don't hate CBD.  They just want there to be more study on what CBD does to the liver and how it might effect other medications a person is taking.  Be mindful in your cannabinoid use and have a listen.